Antinociceptive activity of the endogenous fatty acid amide, palmitylethanolamide
A Calignano, G La Rana, D Piomelli - European journal of pharmacology, 2001 - Elsevier
The endogenous fatty acid ethanolamide, palmitylethanolamide, alleviated, in a dose-
dependent manner, pain behaviors elicited in mice by injections of formalin (5%,
intraplantar), acetic acid (0.6%, 0.5 ml per animal, intraperitoneal, ip), kaolin (2.5 mg per
animal, ip), and magnesium sulfate (120 mg per kg, ip). The antinociceptive effects of
palmitylethanolamide were prevented by the cannabinoid CB2 receptor antagonist
SR144528 [N-([1s]-endo-1.3. 3-trimethylbicyclo [2.3. 1] heptan-2-yl)-5-(4-chloro-3 …
dependent manner, pain behaviors elicited in mice by injections of formalin (5%,
intraplantar), acetic acid (0.6%, 0.5 ml per animal, intraperitoneal, ip), kaolin (2.5 mg per
animal, ip), and magnesium sulfate (120 mg per kg, ip). The antinociceptive effects of
palmitylethanolamide were prevented by the cannabinoid CB2 receptor antagonist
SR144528 [N-([1s]-endo-1.3. 3-trimethylbicyclo [2.3. 1] heptan-2-yl)-5-(4-chloro-3 …
以上显示的是最相近的搜索结果。 查看全部搜索结果